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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1A
All Species:
37.12
Human Site:
T282
Identified Species:
62.82
UniProt:
Q16623
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16623
NP_004594.1
288
33023
T282
L
G
I
V
I
A
S
T
V
G
G
I
F
A
_
Chimpanzee
Pan troglodytes
XP_001146754
288
33051
T282
L
G
I
V
I
A
S
T
V
G
G
I
F
A
_
Rhesus Macaque
Macaca mulatta
NP_001028037
288
32987
T282
L
G
I
V
I
A
S
T
V
G
G
I
F
A
_
Dog
Lupus familis
XP_849756
293
33456
T287
L
G
I
V
I
A
S
T
F
G
G
I
F
G
_
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
T282
L
G
I
I
I
A
S
T
I
G
G
I
F
G
_
Rat
Rattus norvegicus
P32851
288
33049
T282
L
G
I
I
I
A
S
T
I
G
G
I
F
G
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
T310
L
G
I
V
I
A
S
T
F
G
G
I
F
G
_
Frog
Xenopus laevis
NP_001086322
286
32704
T280
L
A
I
V
I
A
S
T
I
G
G
I
F
A
_
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S281
L
G
V
V
L
R
S
S
I
G
G
T
L
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y285
L
G
I
L
A
A
S
Y
V
S
S
Y
F
M
_
Honey Bee
Apis mellifera
XP_393760
291
33455
L284
L
P
L
L
L
L
L
L
L
L
L
F
S
T
M
Nematode Worm
Caenorhab. elegans
O16000
291
33234
G279
T
G
V
I
L
I
T
G
L
I
I
F
I
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRV7
306
34701
V293
L
I
I
I
I
I
T
V
I
S
V
L
K
P
W
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
S289
V
V
V
V
V
V
P
S
V
V
E
T
R
K
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.9
93.1
N.A.
98.2
98.6
N.A.
N.A.
85.7
67.3
82.9
N.A.
70
69.4
63.2
N.A.
Protein Similarity:
100
95.4
98.9
94.5
N.A.
98.9
99.3
N.A.
N.A.
89.8
85.7
93.4
N.A.
83.1
81.4
80
N.A.
P-Site Identity:
100
100
100
85.7
N.A.
78.5
78.5
N.A.
N.A.
85.7
85.7
40
N.A.
50
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
85.7
N.A.
92.8
92.8
N.A.
N.A.
85.7
92.8
66.6
N.A.
57.1
33.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.3
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
14.2
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
42.8
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
65
0
0
0
0
0
0
0
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
15
65
0
15
% F
% Gly:
0
72
0
0
0
0
0
8
0
65
65
0
0
36
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
72
29
65
15
0
0
36
8
8
58
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
86
0
8
15
22
8
8
8
15
8
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
72
15
0
15
8
0
8
0
0
% S
% Thr:
8
0
0
0
0
0
15
58
0
0
0
15
0
8
0
% T
% Val:
8
8
22
58
8
8
0
8
36
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% _